Literature summary extracted from

Fung, K.M.; Samara, E.N.; Wong, C.; Metwalli, A.; Krlin, R.; Bane, B.; Liu, C.Z.; Yang, J.T.; Pitha, J.V.; Culkin, D.J.; Kropp, B.P.; Penning, T.M.; Lin, H.K.
Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma (2006), Endocr. Relat. Cancer, 13, 169-180.

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.239	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.1.239	endothelial cell	-	Homo sapiens	-
1.1.1.239	perineurium	-	Homo sapiens	-
1.1.1.239	prostate gland	androgen target tissues	Homo sapiens	-
1.1.1.239	prostatic urethra	-	Homo sapiens	-

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.239	AKR1C3	multi-functional enzyme that possesses 3alpha-, 17beta-, 20alpha-hydroxysteroid dehydrogenase, as well as prostaglandine F synthase activities and catalyzes androgen, estrogen, progestin and prostaglandin metabolism. It is a member of the aldo-keto reductase superfamily.	Homo sapiens
1.1.1.239	type 2 3alpha-hxdroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase	-	Homo sapiens

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Release 2023.1 (January 2023)